Unilateral versus Bilateral Laparoscopic Ovarian Drilling in Clomiphene Citrate Resistant Cases of Polycystic Ovarian Syndrome: A Randomized Controlled Study

Sahar Saeed Elhalfawy, Obstetrics and Gynecology Department, Faculty of Medicine, University of Tanta, Tanta, Egypt.Follow
Mostafa Zein- Elabedeen Mohammed, Obstetrics and Gynecology Department, Faculty of Medicine, University of Tanta, Tanta, Egypt.
Ayman Shehata Dawood, Obstetrics and Gynecology Department, Faculty of Medicine, University of Tanta, Tanta, Egypt.
Mai Nabil Ageez, Obstetrics and Gynecology Department, Faculty of Medicine, University of Tanta, Tanta, Egypt.

Article Type

Original Study

Subject Area

Obstetrics and Gynecology

Abstract

Background: Laparoscopic Ovarian Drilling (LOD) is superior to gonadotropins as it induces mono-ovulation, hence eliminating the potential risks linked to multiple pregnancies or ovarian hyperstimulation syndrome (OHSS).

Aim: To contrast the efficiency of unilateral laparoscopic ovarian drilling (ULOD) and bilateral ovarian drilling (BLOD) in treating clomiphene citrate (CC) resistant instances of polycystic ovarian syndrome (PCOS) according to clinical responses, change in biochemical parameters, follicle stimulating hormone (FSH), anti-mullerian hormone (AMH), luteinizing hormone (LH), ovulation rate over six months.

Methods: This Randomized Controlled Work was performed on 140 participants aged from 25 to 35 years old, with PCOS, infertile women who have CC resistant PCOS and normal semen analysis in the husband. Patients were allocated into two equal group. Group U: patients underwent unilateral LOD and Group B: underwent bilateral LOD.

Results: Menstrual pattern, FSH, LH before and after operation were insignificantly various among the two groups. LH, AMH, AFC was significantly decreased following operation compared to prior the operation in both groups (P

Conclusions: LOD is efficient therapy for menstrual irregularities in PCOS, and there is no notable distinction in effectiveness between unilateral and bilateral LOD. ULOD is equally successful as BLOD in treating instances of PCOS.

IRB Number

34896/9/21

Keywords

Unilateral, Bilateral, Laparoscopic Ovarian Drilling, Clomiphene Citrate, Polycystic Ovarian Syndrome

Recommended Citation

Elhalfawy, Sahar Saeed; Mohammed, Mostafa Zein- Elabedeen; Dawood, Ayman Shehata; and Ageez, Mai Nabil (2024) "Unilateral versus Bilateral Laparoscopic Ovarian Drilling in Clomiphene Citrate Resistant Cases of Polycystic Ovarian Syndrome: A Randomized Controlled Study," Journal of Medicine in Scientific Research: Vol. 8: Iss. 1, Article 9.
DOI: https://doi.org/10.59299/2537-0928.1422