Role of magnetic resonance imaging (MRI) in evaluating the Indeterminate Breast Lesions

Jehan Ibrahim M. AlTohamy, Lecturer of Radiology, National Institute of Urology and Nephrology (NIUN) And Armed Forces Collage of Medicine (AFCM)Follow
Nivine Abdel Moneim Chalabi, Professor of Radiology, Ain Shams University (ASU)
Mohamed Amr Farouk, Assisstant professor, Military Medical Academy (MMA)
Mina Awny Moawad, Military Medical Academy (MMA)
Shrouk Mohamed Awadallah, Lecturer of radiology, Ain shams University (ASU) and Armed forces Collage of medicine (AFCM)

Article Type

Original Study

Subject Area

Diagnostic and Interventional Radiology

Abstract

Background: the number of women who are diagnosed with breast cancer (BC) continues to rise, making it the utmost public cause of cancer death among ladies globally. It has been proposed that high-risk individual's get breast MRIs, which are the most sensitive breast cancer screening method that does not use ionizing radiation. Aim and objectives; This research effort assesses breast MRI in order to clarify the Breast Imaging Reporting and Data System categorization of indeterminate mammography or ultrasonography examines as well as evaluate the diagnostic reliability of MRI in assessing lesions discovered on screening or diagnostic mammography or ultrasonography that are BIRADS 3 or 4. The goal of the research is to minimize the mortality rate associated with breast cancer. Subjects & methods; This Diagnostic accuracy observational analytical cross-sectional trial was done on 38 patients presented with BIRADS 3 & 4 lesions by conventional ultrasound & mammography at Department of Radiology, Armed Forces College of Medicine, Cairo, Egypt. The duration of the study was from 1/1/2023 to 31/10/2023. Result: Regarding Time of maximum enhancement as detected in MRI, considering that absence enhancement and late enhancement at10,7, and 4minutes are signs of Benign lesions and maximum enhancement at 2 and 1 minutes are signs of Malignant lesions, Sensitivity was 95%, Specificity was 77.78% and Accuracy was 86.84%. Regarding Threshold of enhancement as detected in MRI, considering that absence of enhancement and threshold enhancement less than 60 are signs of Benign lesions and threshold of enhancement more than 60 are signs of Malignant lesions, Sensitivity was 69.70%, Specificity was 100% and Accuracy was 73.68%. Essential imaging tool breast MRI is increasingly employed in daily practice. Conclusion: Stellate shape, non-defined lesion margins, skin thickening, earlier time to enhancement, earlier peak, earlier washout, type II & III enhancement curves, maximum enhancement at 2 & 1 minutes, ADC and MRS were identified as significant predictors for breast cancer malignancy.

IRB Number

IORG0008659

Keywords

magnetic resonance imaging (MRI), X-ray mammography, Breast Imaging-Reporting and Breast cancer (BC), American College of Radiology (ACR), Database System (BIRADS)

Recommended Citation

AlTohamy, Jehan Ibrahim M.; Chalabi, Nivine Abdel Moneim; Farouk, Mohamed Amr; Moawad, Mina Awny; and Awadallah, Shrouk Mohamed (2024) "Role of magnetic resonance imaging (MRI) in evaluating the Indeterminate Breast Lesions," Journal of Medicine in Scientific Research: Vol. 7: Iss. 4, Article 2.
DOI: https://doi.org/10.59299/2537-0928.1401