Oral collagen supplementation in 2nd degree burn and chronic pressure ulcers

Wesam Ibrahem Homouda, Department of plastic Surgery, Banha Teaching hospital, Banha, EgyptFollow
Helmy ahmed Soliman, Department of plastic Surgery, Mataria Teaching hospital, Cairo, Egypt
Esayed Hussien Elmokadem, Department of General Surgery, Banha Teaching hospital, Banha, Egypt

Article Type

Original Study

Subject Area

Plastic Surgery

Abstract

Background: Healing of wounds requires adequate intake of protein, iron, Vitamin-C and zinc. In case of deficiency in the dietary intake, supplements may be prescribed. Collagen-peptide supplements can enhance skin hydration, elasticity, and reduce wrinkles. Burns, caused by various agents, severely damage skin layers. Pressure ulcers occur when prolonged pressure on the skin leads to tissue ischaemia, disrupting nutrition and oxygen supply, resulting in tissue necrosis. Systematic reviews show that oral collagen, either intact or hydrolyzed, effectively improves skin health.

Objectives: This article aim to evaluate the effect of oral collagen intake as a healing promoting supplementation in management of 2^nd degree burn and chronic pressure ulcers.

Patient and method: This study was implemented on 80 patients from 15 to 50 years old, from Qalyobia and Cairo governorates including rural and urban areas. Patients will be divided into two groups 1^st group of burn patients will be divided into two subgroups (A) will receive oral collagen supplementation added to oral treatment (B) will not receive oral collagen supplementation.2^nd group of chronic pressure ulcers will be divided into two subgroups (A) will receive oral collagen supplementation added to oral treatment (B) will not receive oral collagen supplementation.

Results: Regarding to significant value Socioeconomic state was much higher in G1 (A) (p-value=0.001*) and in in G2 (A) (p-value=0.001*). Patient compliance was much higher in G1 (A) (p-value=0.002*) and in in G2 (A) (p-value=0.001*). Burn degree, Type of overlying dressing, Frequency of dressing, Size of wound and Depth of wound shows non-significant differences Side effects of oral medication shows non-significant difference in G1and a significant difference in G2 (p-value=0.019*). Rapid healing was recorded for G 1 (A) (8.30±2.74d) and in G 2 (A) (12.00±1.34d). (68/80) of the patients or their relatives were satisfied about the results and they were comfortable with oral supplementation intake.

Conclusion: Oral collagen supplementation had been found to accelerate wound healing and improves the outcome and patient satisfaction.

IRB Number

HB000117

Keywords

2nd degree burn; chronic pressure ulcers; oral collagen; healing promotor

Recommended Citation

Homouda, Wesam Ibrahem; Soliman, Helmy ahmed; and Elmokadem, Esayed Hussien (2024) "Oral collagen supplementation in 2nd degree burn and chronic pressure ulcers," Journal of Medicine in Scientific Research: Vol. 7: Iss. 4, Article 12.
DOI: https://doi.org/10.59299/2537-0928.1410