Bone grafting with PRP and dental implantation for unilateral alveolar cleft patients

Wesam Ibrahem Homouda, Department of plastic Surgery, Banha Teaching hospital, Banha, EgyptFollow
Helmy ahmed Soliman, Department of plastic Surgery, Mataria Teaching hospital, Cairo, Egypt
Mohamed Amr Hamdy Salem, Department of oral medicine & periodontology, Banha Teaching hospital, Banha, Egypt

Article Type

Original Study

Subject Area

Plastic Surgery

Abstract

Background: Cleft lip and palate (CLP) deformity is the most common congenital craniofacial anomaly, often treated with Alveolar Bone Grafting (ABG) in patients with alveolar clefts. Application of Platelet Rich Plasma (PRP) enhances healing by releasing high concentrations of cytokines from platelets. Over the past century, the treatment for alveolar clefts had been evolved, with the current standard being autologous cancellous bone grafts from iliac crest in 6 to 11-year-old patients during the mixed dentition period. Dental implant has role of holding dental prosthesis, preventing pronounced bone atrophy and loading the augmentation material in cleft area.

Objectives: The objective of this work is to evaluate the effectiveness of Platelet Rich Plasma (PRP) injection with bone grafting and dental implantation in alveolar clefts patients.

Patient and method: This study will be implemented on 30 patients from 15 to 20 years old, from Qalyobia and Cairo governorates including rural and urban areas.

Results: Regarding to significant value mobility was much higher in G1 (p-value=0.001*). Time of loading was much shorter in G1 (p-value=0.001*). Time of osteointegration was much higher in G1 (p-value=0.001*). Sex, Patient compliance, Oral Hygiene, Infection, Failure of implant, shows non-significant differences. Complication and time of healing shows non-significant difference. Time of loading was recorded for G 1 (7.07±1.10m) and in G 2 (10.13±1.19m). (27/30) of the patients were satisfied about the results.

Conclusion: Patient characteristics, infection rates, implant success, complications, and satisfaction were similar between groups. However, PRP injection led to a shorter time for implant loading and a longer time for osteointegration compared to the non-PRP group. Dental professionals should consider these timing differences when planning treatments, as they can influence outcomes and treatment timelines.

IRB Number

HB000116

Keywords

Cleft lip palate; bone grafting;dental implantation; Platelet-rich plasma

Recommended Citation

Homouda, Wesam Ibrahem; Soliman, Helmy ahmed; and Salem, Mohamed Amr Hamdy (2024) "Bone grafting with PRP and dental implantation for unilateral alveolar cleft patients," Journal of Medicine in Scientific Research: Vol. 7: Iss. 4, Article 11.
DOI: https://doi.org/10.59299/2537-0928.1409