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Article Type

Original Study

Abstract

Background Blindness is the end result of diabetic macular edema (DME). A 577-nm diode laser is the most frequently used one in ophthalmology. This study aimed to assess the effect of grid-diode laser application on the central macular thickness and ganglion-cell complex in management of clinically significant macular edema. Methods This study was performed on 95 eligible eyes. Complete ophthalmologic examination was performed, including best-corrected visual acuity with the use of ETDRS charts, measuring intraocular pressure, using slit lamp for biomicroscopic examination, fluorescein angiography, and fundus examination. Follow-up examinations, with complete ophthalmologic examination, were scheduled at 1 and 3 months after grid-diode laser application. Results and conclusions The study revealed significant improvement in the visual acuity after 3-month follow-up as well as significant decrease in central macular thickness and ganglion-cell complex at both 1- and 3-month follow-up visits. And in conclusion, an 810-nm grid-diode laser can be considered as an effective treatment for DME with improvement in visual acuity and reduction in thickness on optical coherence tomography. However, longer follow-up periods are needed to confirm the benefit of a 577-nm diode laser for DME. Its effect in previously untreated eyes needs also to be assessed in a randomized trial against other current treatment options, including conventional argon laser.

Keywords

Central macular thickness, diabetic macular edema, diode laser, ganglion-cell complex, grid-laser treatment

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