The role of sildenafil in perioperative management of patients with pulmonary hypertension undergoing lower limb vascular surgery

Authors

Ashraf A.H M. Soliman, National Heart InstituteFollow
Wael Abd Elateif El Hakeem, National Heart Institute

Article Type

Original Study

Abstract

Objective To assess the role of sildenafil in perioperative management of patients with pulmonary hypertension undergoing lower limb vascular surgery. Patients and methods Twenty-four patients with pulmonary hypertension presented for lower limb vascular surgery were divided into equal groups, group 1 and group 2, each group having 12 patients. Result As regards demographic data, mean arterial pressure, and heart rate there were no statistically significant differences between both groups. As regards PaO₂ measured in arterial blood gases, pulmonary artery pressure, and ejection fraction, there was statistically significant differences between both groups. Conclusion We found that sildenafil has a unique effect in reducing pulmonary artery pressure, improving oxygenation, ejection fraction, and ICU stay.

Keywords

Lower limb vascular surgery, pulmonary hypertension, sildenafil

Recommended Citation

M. Soliman, Ashraf A.H and Elateif El Hakeem, Wael Abd (2022) "The role of sildenafil in perioperative management of patients with pulmonary hypertension undergoing lower limb vascular surgery," Journal of Medicine in Scientific Research: Vol. 5: Iss. 3, Article 11.
DOI: https://doi.org/10.4103/jmisr.jmisr_68_21