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Article Type

Original Study

Abstract

Background Coronary artery disease is the most common of the cardiovascular diseases that can be treated with coronary artery bypass grafting (CABG) surgery, with either on-pump or off-pump technique. In this study, we aimed to compare the early results of isolated CABG, using on-pump and off-pump techniques, in patients with preoperative mild-to-moderate elevation of serum creatinine (1.6–2.5 mg/dl) level who did not require maintenance dialysis to support renal function. Patients and methods This prospective nonrandomized study included 60 patients who complained of symptoms of coronary artery disease and subsequently underwent myocardial revascularization at Cardiothoracic Surgery Department, Shebin El-Kom Teaching Hospital, Menoufia, Egypt, between June 2017 and August 2018. Results In group A (the on-pump group), the mean age was 73.40 ± 6.38 years, whereas in group B (the off-pump group), the mean age was 72.87 ± 9.62 years. The mean of total pump time was 112.40 ± 37.80 min and the mean of total ischemic time was 67.50 ± 24.18 min Regarding the operation time, the mean of on-pump CABG operation time was 234.60 ± 57.54 min, and 273.77 ± 43.07 min for the off-pump CABG operation, with statistically significant difference (P = 0.004). The mean time of ICU stay was 4.66 ± 3.36 days in the on-pump CABG and 3.70 ± 2.15 days in the off-pump CABG group, with no statistically significant difference between the two groups (P = 0.191). Conclusion Regarding postoperative renal dysfunction and need for dialysis, results were in favor of the off-pump technique. Renal function is better preserved in patients undergoing off-pump CABG than those undergoing on-pump CABG.

Keywords

Coronary artery disease, off-pump coronary artery bypass, on-pump coronary artery bypass grafting, renal impairment

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