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Article Type

Original Study

Abstract

Aim and Background Congenital heart diseases constitute a major category of disorders associated with pulmonary hypertension in atrial septal defect there is tendency to repair essentially all large defect except some of those with severe obstructive pulmonary vascular diseases. in this study the isoproterenol is used for assessment of patients with atrial septal defect, with elevated pulmonary / systemic vascular resistance ratio. Methods and Results 100 cases with atrial septal defect, with pulmonary hypertension received isoproterenol infusion. Haemodynamic findings found among all patients with atrial septal defect before and after isoproterenol infusion. There is a significant in pulmonary blood flow after isoproterenol infusion (from 5.34455 + 0.730 to 6.3300 + 0.870 liter/minute P < 0.001). Conclusion Isoproterenol is a successful and reliable pulmonary vasodilator that can be used to predict the reversible element of pulmonary hypertension in patient with left to right shunts (ASD) patients.

Keywords

Atrial septal defects, isoproterenol infusion, Pulmonary vascular resistance

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