A Comparative Study of Clinical Profile of Hospitalized COVID-19 Patients in Relation to Their Vaccination Status

Nisha Kaithwas, Department of Psychiatry, Nandkumar Singh Chouhan Government Medical College Khandwa, MPFollow
Garima Agrawal Varshney, Department of Paediatrics, Nandkumar Singh Chouhan Government Medical College Khandwa, MPFollow
Mohit Garg, Department of Medicine, Nandkumar Singh Chouhan Government Medical College Khandwa, MPFollow
Piyush Mishra Statistician, Department of Community Medicine, Nandkumar Singh Chouhan Government Medical College Khandwa, MPFollow
Soumitra Sethia, Department of Community Medicine, Nandkumar Singh Chouhan Govt. medical College, Khandwa Indore, MP INDIAFollow

Article Type

Original Study

Subject Area

Psychiatry

Abstract

Background: The clinical picture, outcome of Covid-19 infection and vaccine effectiveness vary in different individuals. These may depend on multiple variables like age, sex, comorbidities, and immune status against the virus and in general. Objective: To describe demography, clinical profile, vaccination status and its impact on clinical outcome of hospitalized Covid-19 patients. Methods: This retrospective study was conducted on hospitalized Covid-19 patients of N.S.C.G.M.C. Khandwa, a tertiary care centre from central India. We studied 188 Covid-19 positive admitted patients’ demographic profile, clinical profile, co-morbidity, vaccination status, clinical outcome and association of these variables to their vaccination status during second Covid-19 wave in India from 1st April 2021 to 30th June 2021. Results: The mean age of study participants was 54.1 years and majority (76.5%) were male. Most patients (71.8%) were unvaccinated and 47.9% patients had co-morbid conditions, most common was diabetes (28.9%) followed by hypertension (25.6%). Unvaccinated patients had severe lung infection (72%). There was statistically significant difference between vaccinated & unvaccinated patients in terms of severity of infection, comorbidity, mean baseline SpO2 at admission and need of supplemental oxygen. Conclusion: Vaccination decreases severity of infection and need for supplemental oxygen significantly.

IRB Number

Institutional ethics committee approval number is –No.39//IEC/NSCGMCK/2022, date:01/04/2022

Keywords

Covid-19, Vaccine, Hospitalization, Clinical Profile, Severity

Recommended Citation

Kaithwas, Nisha; Varshney, Garima Agrawal; Garg, Mohit; Mishra, Piyush Statistician; and Sethia, Soumitra (2023) "A Comparative Study of Clinical Profile of Hospitalized COVID-19 Patients in Relation to Their Vaccination Status," Journal of Medicine in Scientific Research: Vol. 6: Iss. 1, Article 2.
DOI: https://doi.org/10.59299/2537-0928.1002